Infirmière Parler à Patient
Therapeutics for
Poorly Sensitive Cancers

Our Company

BiPER Therapeutics is a preclinical-stage biotech company founded in 2021 to develop and commercialize novel therapeutics. We are developing a first-in-class pipeline of small molecules targeting the global metabolism of cancer. The company’s lead compound, BPR001, is a first-in-class small molecule therapeutic targeting BiP, an oncogenic protein shown to have a critical role in cancer through the modulation of the endoplasmic reticulum stress.

New Therapeutic Solutions 

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Resistance to standard chemotherapeutic treatments and poor responses to immune-based therapies represent major challenges in cancer treatment as many patients respond poorly or not at all to currently available treatment options.

BiPER Therapeutics aims to bridge this important treatment gap by developing novel therapeutic solutions based on these core principles: 


  • Targeting the global metabolism of cancer cells

  • Modulating the Endoplasmic Reticulum Stress (ER stress) : 
    a pathway involved in cancer treatment resistance

  • Discovery and development of our BPR series of First-In-Class small molecules selectively targeting BiP/GRP78 :
    a key chaperone protein involved in ER stress

  • Selectively activating cell death in cancer cells and increasing recognition by the immune system in treatment-resistant as well as sensitive cancers

Founders & Executive Team

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Mehdi Chelbi


Co-Founder & CEO

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Biotech - Pharma - CRO
Corporate & Drug Development Experience 

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Zaki Sellam


& Executive Chairman

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Entrepreneurship & Drug Development Expertise

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Stephane Rocchi

PhD - Research Director Inserm



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Expertise in Biology and Translational Research in Oncology @ C3M

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Expertise in Medicinal Chemistry, Drug Design and Pharmacology @ICN

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Cyril Ronco

PhD - MC - HDR



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Expertise in Medicinal Chemistry, Drug Design and Pharmacology @ICN

Rachid Benhida

PhD - Research Director CNRS




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Will attend several conferences in 2022 stay tuned

Ecosystem & Partners

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11 Rue de l'Académie

67000 Strasbourg